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KMID : 0857020160310010005
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Kosin Medical Journal
2016 Volume.31 No. 1 p.5 ~ p.10
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Uterine cancer and ezrin expression
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Kim Yeon-Suk
Kim Tae-Hee
Lee Hae-Hyeog
Kim Heung-Yeol
Jang Dah-Yae
Lee A-Rum
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Abstract
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Today, almost 20% of female cancers are gynecological in nature. In particular, uterine cervical cancer and endometrial cancer (which have been intensively studied) seriously compromise female health. One of the ezrin-radixin-moesin (ERM) proteins, ezrin, has been associated with cancer in prior studies, including the two cancers mentioned above. Ezrin expression increases, as does the expression of other factors, in uterine cervical cancer; ezrin may promote cancer development by influencing the actions of the other factors. Also, an increase in ezrin level contributes to the development of diseases such as endometrial cancer.
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KEYWORD
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Cervical intraepithelial neoplasia, endometrial neoplasms, neurofibronin 2, uterine cervical neoplasms
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